Rosanna Vaschetto


Short curriculum vitae Rosanna Vaschetto


1.       Personal Information:

Date and Place of Birth: 14/08/1977, Alba, Italy. Address: Via Scavini 2A, 28100, Novara, Italy. Tel: +39334 2724811 email:  Languages: Italian, English, Spanish

2.       Academic Degrees

1996 - 2002: M.D. Graduated cum laude from the University of Eastern Piedmont, Novara-Italy

2002: Medical License

2002-2006: Specialization in Anesthesia and Intensive Care Medicine -70/70 cum laude, University of Eastern Piedmont, Novara, Italy

2006-2008 PhD of “Clinical and Experimental Medicine” under the supervision of Prof. F. Della Corte and Prof. P. Navalesi

2014: National Scientific Qualification as Associate Professor

2016-Today :biennial master entitled “Master Universitario di II livello in Biostatistica e Metodologia Epidemiologica” under the supervision of Prof. Montomoli, Prof. Magnani

2017: National Scientific Qualification as Full Professor

2017: Associate Professor at the Dipartimento di Medicina Traslazionale, University of Eastern Piedmont, Novara, Italy

3.       Professional Experience

·         December 2008-Today: Staff physician at the Department of Anesthesia and Intensive Care, Maggiore della Carità hospital, Novara, Italy

·         February 2007-February 2008: Research fellow, Department of Intensive Care, Vrije Universiteit Medical Centre, Amsterdam under the supervision of Prof. A.B. Johan Groeneveld and Dr. Frans B. Plötz

·         November 2004-July 2006: Research fellow, Departments of Anesthesia and Critical Care, Division of Respirology, University of Toronto, St. Michael’s Hospital, under the supervision of Prof. H. Zhang and Prof. A.S. Slutsky

·         1999-2002: Research student at the laboratory of Immunology, University of Eastern Piedmont, Novara, under the supervision of Prof. U. Dianzani. Project: “The T cell activation molecule H4 and the CD28-like molecule ICOS are identical”

·         2001: Summer student at the Centro de Investigaciones Biologicas de Madrid, Departimento de Inmunologia under the supervision of Dr. Josè M. Rojo. Project: “Mechanisms of H4/ICOS costimulation: effects on proximal TCR signals and MAP kinase pathways”

·         2000: Summer student at the Department of Pathology, Washington University School of Medicine in St. Louis under the supervision of Prof. Andrew Shaw. Project: “T-cell activation and lipid rafts”

4.       Miscellaneous

·         From 2006-nowdays: Member of the European Society of Intensive Care Medicine

·         From 2016: Member of the European Respiratory Society

·         1st-8th-14th March, 5th-12th-18th April, 17th May 2008, Torino, Basic Statistic held by Dr. Rossi and Dr. Boffelli Laboratorio di Epidemiologia Clinica, Istituto di Ricerche Farmacologiche Mario Negri, Ranica (BG)

·         27 Jannuary-26 February  2014 “Methodology of Research in Emergency and Disaster Medicine: what the researcher need to know” held by Prof. Jeffrey Michael Franc, clinical professor of Emergency Medicine, University of Alberta, Canada

·         Reviewer for many journals (CCM, ICM, BMC Neurology, Journal of Thoracic Disease)

5.       Awards

·         Vaschetto R. Non invasive ventilation via  helmet  in  weaning  patients  with  hypoxemic  acute respiratory failure. Awarded 2009 European Society of Intensive Care Medicine, Clinical Research Award. Vienna, October 2009

·         Vaschetto R, Kuiper JW, Della Corte F, Groeneveld JAB, Plötz FB. Inhibition of Poly(adenosine diphosphate-ribose) polymerase attenuates ventilator-induced lung injury and preserves kidney function. Awarded best oral presentation NVIC Nederlandse Intensivistendagen 2008. Ede, February 2008

·         Vaschetto R.  The role of Poly(ADP-Ribose) polymerase 1 (PARP-1) in acute renal failure associated with ventilator induced lung injury. Awarded 2006 European Society of Intensive Care Medicine, Basic Science Award. Barcelona October 2006

·         Vaschetto R, Khine AA, Slutsky AS, Zhang H. Novel mechanisms of sensing LPS by lung epithelial cells. Awarded best oral presentation Critical Care Research Day. Toronto June 2006; Awarded best poster presentation Respirology Research Day. Toronto June 2006; Awarded best oral presentation Physiology Research Day. Toronto May 2006

·         Vaschetto R, Khine AA, Slutsky AS, Zhang H. A new strategy to recognize LPS by lung epithelial cells. Awarded best oral presentation Critical Care Research Day. Toronto June 2005


 1.       Vaschetto R,  Longhini F. Navalesi P. Acute noninvasive ventilation. In: European Respiratory Society Monograph 2016.  Chapter 14. ISBN: 978-1-84984-052-1

 2.       Navalesi P, Colombo D, Cammarota G, Vaschetto R. Neurally adusted ventilator assist. In: European Respiratory Society Monograph 2012.  p. 116-123. ISSN:1025-448x

 3.       Navalesi P, Vaschetto R, Messina A. (2010). Emerging modes for non-invasive ventilation. In: Elliot M, Nava S, Schonhofer B. Non-invasive Ventilation and Weaning: Principles and Practice. p. 36-41, London:Edward Arnold Ltd, ISBN: 9780340941522

 4.       Vaschetto R, Plötz FB, Groeneveld ABJ (2008). Role of poly(ADP-ribose) polymerase in acute kidney injury.. In: Yearbook of intensive care and emergency medicine. p. 559-567, BRUSSELS:Jean-Luis Vincent

 5.       Vaschetto R, Haitsma JJ, Zhang H (2006). Genetics and molecular biology in acute lung injury . In: Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E. . p. 11-17, Springer Milan, ISBN: 978-88-470-0570-9, doi: 10.1007/978-88-470-0571-6_2


 Original peer-reviewed papers (H Index 16)

1.         Mahul M, Jung B, Galia F, Molinari N, de Jong A, Coisel Y, Vaschetto R, Matecki S, Chanques G, Brochard L, Jaber S. Spontaneous breathing trial and post-extubation work of breathing in morbidly obese critically ill patients. Crit Care. 2016 Oct 27;20(1):346.

2.         Cammarota G, Longhini F, Perucca R, Ronco C, Colombo D, Messina A, Vaschetto R, Navalesi P. New Setting of Neurally Adjusted Ventilatory Assist during Noninvasive Ventilation through a Helmet. Anesthesiology. 2016 Dec;125(6):1181-1189

3.         Olivieri C, Longhini F, Cena T, Cammarota G, Vaschetto R, Messina A, Berni P, Magnani C, Della Corte F, Navalesi P. New versus Conventional Helmet for Delivering Noninvasive Ventilation: A Physiologic, Crossover Randomized Study in Critically Ill Patients. Anesthesiology. 2016 Jan;124(1):101-8

4.         Vaschetto R, Frigerio P, Sommariva M, Boggero A, Rondi V, Grossi F, Cavuto S, Nava S, Corte FD, Navalesi P. Evaluation of a systematic approach to weaning of tracheotomized neurological patients: an early interrupted randomized controlled trial. Ann Intensive Care. 2015 Dec;5(1):54

5.         Vaschetto R, Corradi M, Goldoni M, Cancelliere L, Pulvirenti S, Fazzini U, Capuzzi F, Longhini F, Mutti A, Della Corte F, Navalesi P. Sampling and analyzing alveolar exhaled breath condensate in mechanically ventilated patients: a feasibility study. J Breath Res. 2015 Nov 19;9(4):047106.

6.         Pisani L, Mega C, Vaschetto R, Bellone A, Scala R, Cosentini R, Musti M, Del Forno M, Grassi M, Fasano L, Navalesi P, Nava S. Oronasal mask versus helmet in acute hypercapnic respiratory failure. Eur Respir J. 2015 Mar;45(3):691-9.

7.         Kuiper JW, Groeneveld AB, Haitsma JJ, Smeding L, Begieneman MP, Jothy S, Vaschetto R, Plötz FB. Injurious mechanical ventilation causes kidney apoptosis and dysfunction during sepsis but not after intra-tracheal acid instillation: an experimental study. BMC Nephrol. 2014 Jul 29;15:126.

8.       Maggiore SM, Idone FA, Vaschetto R, Festa R, Cataldo A, Antonicelli F, Montini L, De Gaetano A, Navalesi P, Antonelli M. Nasal high-flow versus Venturi mask oxygen therapy after extubation. Effects on oxygenation, comfort, and clinical outcome. Am J Respir Crit Care Med. 2014 Aug 1;190(3):282-8.

9.       Vaschetto R, Navalesi P, Clemente N, Boggio E, Valsecchi S, Olivieri C, Soluri MF, Kroumova V, Fonio P, Dinatale C, Borrè S, Fortina G, Umberto D, Della Corte F, Chiocchetti A. Osteopontin induces soluble urokinase-type plasminogen activator receptor production and release. Minerva Anestesiol. 2015 Feb;81(2):157-65.

10.      Vaschetto R, De Jong A, Conseil M, Galia F, Mahul M, Coisel Y, Prades A, Navalesi P, Jaber S. Comparative evaluation of three interfaces for non-invasive ventilation: a randomized cross-over design physiologic study on healthy volunteers. Crit Care. 2014 Jan 3;18(1):R2. doi: 10.1186/cc13175.

11.      Vaschetto R, Cammarota G, Colombo D, Longhini F, Grossi F, Giovanniello A, Corte FD, Navalesi P. Effects of Propofol on Patient-Ventilator Synchrony and Interaction During Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist. Crit Care Med. 2014 Jan;42(1):74-82.

12.      Vaschetto R, Navalesi P. Failure of noninvasive ventilation: one more chance? Crit Care Med. 2013 Feb;41(2):675.

13.      Nicolini A, Tonveronachi E, Navalesi P, Antonelli M, Valentini I, Melotti RM, Pigna A, Carrassi A, Righini P, Ferrari Bravo M, Pelosi P, Nicoli F, Cosentini R, Vaschetto R, Faenza S, Nava S. Effectiveness and predictors of success of noninvasive ventilation during H1N1 pandemics: a multicenter study. Minerva Anestesiol. 2012 Dec;78(12):1333-40.

14.      Vaschetto R, Turucz E, Dellapiazza F, Guido S, Colombo D, Cammarota G, Della Corte F, Antonelli M, Navalesi P. Noninvasive ventilation after early extubation in patients recovering from hypoxemic acute respiratory failure: a single-centre feasibility study. Intensive Care Med. 2012 Oct;38(10):1599-606.

15.      Vaschetto R, Kroumova V, Olivieri C, Bergamaschi V, Cancelliere L, Borrè S, Fortina G, Navalesi P, Della Corte F. Early diagnosis of invasive pulmonary aspergillosis in a young immunocompetent patient. New Microbiol. 2012 Jan;35(1):77-82. Epub 2012 Jan 10.

16.      Kuiper JW, Plötz FB, Groeneveld AJ, Haitsma JJ, Jothy S, Vaschetto R, Zhang H, Slutsky AS. High tidal volume mechanical ventilation-induced lung injury in rats is greater after acid instillation than after sepsis-induced acute lung injury, but does not increase systemic inflammation: an experimental study. BMC Anesthesiol. 2011 Dec 28;11:26. doi: 10.1186/1471-2253-11-26.

17.      Cammarota G, Olivieri C, Costa R, Vaschetto R, Colombo D, Turucz E, Longhini F, Della Corte F, Conti G, Navalesi P. Noninvasive ventilation through a helmet in postextubation hypoxemic patients: physiologic comparison between neurally adjusted ventilatory assist and pressure support ventilation. Intensive Care Med. 2011 Dec;37(12):1943-50. doi: 10.1007/s00134-011-2382-2.

18.      Kuiper JW, Vaschetto R, Della Corte F, Plötz FB, Groeneveld AB. Bench-to-bedside review: Ventilation-induced renal injury through systemic mediator release--just theory or a causal relationship? Crit Care. 2011 Aug 16;15(4):228.

19.      Colombo D, Cammarota G, Alemani M, Carenzo L, Barra FL, Vaschetto R, Slutsky AS, Della Corte F, Navalesi P. Efficacy of ventilator waveforms observation in detecting patient-ventilator asynchrony. Crit Care Med. 2011 Nov;39(11):2452-7

20.      Cammarota G, Vaschetto R, Turucz E, Dellapiazza F, Colombo D, Blando C, Della Corte F, Maggiore SM, Navalesi P. Influence of lung collapse distribution on the physiologic response to recruitment maneuvers during noninvasive continuous positive airway pressure. Intensive Care Med. 2011 Jul;37(7):1095-102.

21.      Vaschetto R, Protti A. Biomarkers of sepsis in long-term critically ill patients. Minerva Anestesiol. 2010 Oct;76(10):771-2

22.      Vaschetto R, Kuiper JW, Musters RJ, Eringa EC, Della Corte F, Murthy K, Groeneveld AB, Plötz FB. Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathway. Crit Care. 2010;14(2):R45.

23.      Vaschetto R, Bellotti E, Turucz E, Gregoretti C, Corte FD, Navalesi P. Inhalational anesthetics in acute severe asthma. Curr Drug Targets. 2009 Sep;10(9):826-32.

24.      Brander L, Sinderby C, Lecomte F, Leong-Poi H, Bell D, Beck J, Tsoporis  N, Vaschetto R, Schultz MJ, Parker TG, Villar J, Zhang H, Slutsky AS. Neurally adjusted ventilatory assist decreases ventilator-induced lung injury and non-pulmonary organ dysfunction in rabbits with acute lung injury. Intensive Care Med. 2009 Nov;35(11):1979-89.

25.      Mendola C, Ferrante D, Oldani E, Cammarota G, Cecci G, Vaschetto R, Della Corte F. Thoracic epidural analgesia in post-thoracotomy patients: comparison of three different concentrations of levobupivacaine and sufentanil. Br J Anaesth. 2009 Mar;102(3):418-23.

26.      Vaschetto R, Nicola S, Olivieri C, Boggio E, Piccolella F, Mesturini R, Damnotti F, Colombo D, Navalesi P, Della Corte F, Dianzani U, Chiocchetti A. Serum levels of osteopontin are increased in SIRS and sepsis. Intensive Care Med. 2008 Sep 20.

27.      Kuiper JW, Versteilen AM, Niessen HW, Vaschetto R, Sipkema P, Heijnen CJ, Groeneveld AB, Plötz FB. Production of endothelin-1 and reduced blood flow in the rat kidney during lung-injurious mechanical ventilation. Anesth Analg. 2008 Oct;107(4):1276-83.

28.      Haitsma JJ, Schultz MJ, Hofstra JJ, Kuiper JW, Juco J, Vaschetto R, Levi M, Zhang H, Slutsky AS. Ventilator-induced coagulopathy in experimental Streptococcus pneumoniae pneumonia. Eur Respir J. 2008 Sep 3.

29.      Vaschetto R, Kuiper JW, Chiang SR, Haitsma JJ, Juco JW, Uhlig S, Plötz FB, Corte FD, Zhang H, Slutsky AS. Inhibition of poly(adenosine diphosphate-ribose) polymerase attenuates ventilator-induced lung injury. Anesthesiology. 2008 Feb;108(2):261-8.

30.      Vaschetto R, Groeneveld AB. An update on acute kidney injury after cardiac surgery. Acta Clin Belg Suppl. 2007;(2):380-4.

31.      Vaschetto R, Grinstein J, Del Sorbo L, Khine AA, Voglis S, Tullis E, Slutsky AS, Zhang H. Role of human neutrophil peptides in the initial interaction between lung epithelial cells and CD4+ lymphocytes. J Leukoc Biol. 2007 Apr;81(4):1022-31.

32.      Khine AA, Del Sorbo L, Vaschetto R, Voglis S, Tullis E, Slutsky AS, Downey GP, Zhang H. Human neutrophil peptides induce interleukin-8 production through the P2Y6 signaling pathway.  Blood 2006 Apr 1;107(7):2936-42
33.      Feito MJ, Vaschetto R, Criado G, Sanchez A, Chiocchetti A, Jimenez-Perianez A, Dianzani U, Portoles P, Rojo JM. Mechanisms of H4/ICOS costimulation: effects on proximal TCR signals and MAP kinase pathways. Eur. J. Immunol. 2003 Jan;33(1):204-14.
34.      BuonfiglioD, Bragardo M, Redoglia V, Vaschetto R, Bottarel F, Bonissoni S, Bensi T, Mezzatesta C, Janeway, CA jr, and U. Dianzani. The T cell activation molecule H4 and the CD28-like molecule ICOS are identical.  Eur. J. Immunol. 2000 Dec;30(12):3463-7



Il programma propone un approccio a problematiche cliniche per la gran parte conosciute dagli studenti, affrontate però secondo una metodologia propria delle condizioni di urgenza. Tale metodologia esce dagli schemi tradizionali dell’inquadramento nosografico delle malattie cercando di passare attraverso i criteri di definizione di gravità e di approccio sintomatico posponendo l’obiettivo di una diagnostica raffinata e definitiva.
Il corso inoltre si propone di presentare gli aspetti principali relativi all’anestesia locoregionale e generale e di proporre gli aspetti più rilevanti della gestione clinica del dolore.


Docente: Professoressa Rosanna Vaschetto



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Scuola di Specializzazione in Anestesia e Rianimazione